Teaming Up To Attack Free Radicals: Antibody/Enzyme Combo Protects Transplanted Lungs From Oxidative Stress Damage.

Byline: University of Pennsylvania Health System

PHILADELPHIA, March 23 (AScribe Newswire) -- Researchers based at the University of Pennsylvania School of Medicine have combined the precision of antibodies with the power of an antioxidant enzyme to create a new way to protect transplanted lungs from oxidative stress - also known as free radical damage - before and during transplantation.

Their findings, presented in the April edition of Nature Biotechnology and available online now, demonstrate the therapeutic potential of immunotargeting as a drug delivery system. Oxidative stress causes some degree of damage in 15-20 percent of all transplants and is the leading …